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Pepstatin Brand names, Pepstatin Analogs

Pepstatin Brand Names Mixture

  • No information avaliable

Pepstatin Chemical_Formula

C14H19Cl2NO2

Pepstatin RX_link

http://www.rxlist.com/cgi/generic2/leukeran.htm

Pepstatin fda sheet

Pepstatin FDA

Pepstatin msds (material safety sheet)

Pepstatin MSDS

Pepstatin Synthesis Reference

No information avaliable

Pepstatin Molecular Weight

304.212 g/mol

Pepstatin Melting Point

65 oC

Pepstatin H2O Solubility

1.24E+004 mg/L

Pepstatin State

Solid

Pepstatin LogP

3.25

Pepstatin Dosage Forms

Tablet

Pepstatin Indication

For treatment of chronic lymphatic (lymphocytic) leukemia, malignant lymphomas including lymphosarcoma, giant follicular lymphoma, and Hodgkin's disease

Pepstatin Pharmacology

Chlorambucil is an antineoplastic in the class of alkylating agents and is used to treat various forms of cancer. Alkylating agents are so named because of their ability to add alkyl groups to many electronegative groups under conditions present in cells. They stop tumor growth by cross-linking guanine bases in DNA double-helix strands - directly attacking DNA. This makes the strands unable to uncoil and separate. As this is necessary in DNA replication, the cells can no longer divide. In addition, these drugs add methyl or other alkyl groups onto molecules where they do not belong which in turn inhibits their correct utilization by base pairing and causes a miscoding of DNA. Alkylating agents are cell cycle-nonspecific. Alkylating agents work by three different mechanisms all of which achieve the same end result - disruption of DNA function and cell death.

Pepstatin Absorption

No information avaliable

Pepstatin side effects and Toxicity

No information avaliable

Pepstatin Patient Information

No information avaliable

Pepstatin Organisms Affected

Humans and other mammals