Chlorbutine en es it fr

Chlorbutine Brand names, Chlorbutine Analogs

Chlorbutine Brand Names Mixture

  • No information avaliable

Chlorbutine Chemical_Formula


Chlorbutine RX_link

Chlorbutine fda sheet

Chlorbutine FDA

Chlorbutine msds (material safety sheet)

Chlorbutine MSDS

Chlorbutine Synthesis Reference

No information avaliable

Chlorbutine Molecular Weight

304.212 g/mol

Chlorbutine Melting Point

65 oC

Chlorbutine H2O Solubility

1.24E+004 mg/L

Chlorbutine State


Chlorbutine LogP


Chlorbutine Dosage Forms


Chlorbutine Indication

For treatment of chronic lymphatic (lymphocytic) leukemia, malignant lymphomas including lymphosarcoma, giant follicular lymphoma, and Hodgkin's disease

Chlorbutine Pharmacology

Chlorambucil is an antineoplastic in the class of alkylating agents and is used to treat various forms of cancer. Alkylating agents are so named because of their ability to add alkyl groups to many electronegative groups under conditions present in cells. They stop tumor growth by cross-linking guanine bases in DNA double-helix strands - directly attacking DNA. This makes the strands unable to uncoil and separate. As this is necessary in DNA replication, the cells can no longer divide. In addition, these drugs add methyl or other alkyl groups onto molecules where they do not belong which in turn inhibits their correct utilization by base pairing and causes a miscoding of DNA. Alkylating agents are cell cycle-nonspecific. Alkylating agents work by three different mechanisms all of which achieve the same end result - disruption of DNA function and cell death.

Chlorbutine Absorption

No information avaliable

Chlorbutine side effects and Toxicity

No information avaliable

Chlorbutine Patient Information

No information avaliable

Chlorbutine Organisms Affected

Humans and other mammals