PharmacyCodes



Phenylbuttersaeure-Lost en es it fr

Phenylbuttersaeure-Lost Brand names, Phenylbuttersaeure-Lost Analogs

Phenylbuttersaeure-Lost Brand Names Mixture

  • No information avaliable

Phenylbuttersaeure-Lost Chemical_Formula

C14H19Cl2NO2

Phenylbuttersaeure-Lost RX_link

http://www.rxlist.com/cgi/generic2/leukeran.htm

Phenylbuttersaeure-Lost fda sheet

Phenylbuttersaeure-Lost FDA

Phenylbuttersaeure-Lost msds (material safety sheet)

Phenylbuttersaeure-Lost MSDS

Phenylbuttersaeure-Lost Synthesis Reference

No information avaliable

Phenylbuttersaeure-Lost Molecular Weight

304.212 g/mol

Phenylbuttersaeure-Lost Melting Point

65 oC

Phenylbuttersaeure-Lost H2O Solubility

1.24E+004 mg/L

Phenylbuttersaeure-Lost State

Solid

Phenylbuttersaeure-Lost LogP

3.25

Phenylbuttersaeure-Lost Dosage Forms

Tablet

Phenylbuttersaeure-Lost Indication

For treatment of chronic lymphatic (lymphocytic) leukemia, malignant lymphomas including lymphosarcoma, giant follicular lymphoma, and Hodgkin's disease

Phenylbuttersaeure-Lost Pharmacology

Chlorambucil is an antineoplastic in the class of alkylating agents and is used to treat various forms of cancer. Alkylating agents are so named because of their ability to add alkyl groups to many electronegative groups under conditions present in cells. They stop tumor growth by cross-linking guanine bases in DNA double-helix strands - directly attacking DNA. This makes the strands unable to uncoil and separate. As this is necessary in DNA replication, the cells can no longer divide. In addition, these drugs add methyl or other alkyl groups onto molecules where they do not belong which in turn inhibits their correct utilization by base pairing and causes a miscoding of DNA. Alkylating agents are cell cycle-nonspecific. Alkylating agents work by three different mechanisms all of which achieve the same end result - disruption of DNA function and cell death.

Phenylbuttersaeure-Lost Absorption

No information avaliable

Phenylbuttersaeure-Lost side effects and Toxicity

No information avaliable

Phenylbuttersaeure-Lost Patient Information

No information avaliable

Phenylbuttersaeure-Lost Organisms Affected

Humans and other mammals