Chlorbutin en es it fr

Chlorbutin Brand names, Chlorbutin Analogs

Chlorbutin Brand Names Mixture

  • No information avaliable

Chlorbutin Chemical_Formula

C14H19Cl2NO2

Chlorbutin RX_link

http://www.rxlist.com/cgi/generic2/leukeran.htm

Chlorbutin fda sheet

Chlorbutin FDA

Chlorbutin msds (material safety sheet)

Chlorbutin MSDS

Chlorbutin Synthesis Reference

No information avaliable

Chlorbutin Molecular Weight

304.212 g/mol

Chlorbutin Melting Point

65 oC

Chlorbutin H2O Solubility

1.24E+004 mg/L

Chlorbutin State

Solid

Chlorbutin LogP

3.25

Chlorbutin Dosage Forms

Tablet

Chlorbutin Indication

For treatment of chronic lymphatic (lymphocytic) leukemia, malignant lymphomas including lymphosarcoma, giant follicular lymphoma, and Hodgkin's disease

Chlorbutin Pharmacology

Chlorambucil is an antineoplastic in the class of alkylating agents and is used to treat various forms of cancer. Alkylating agents are so named because of their ability to add alkyl groups to many electronegative groups under conditions present in cells. They stop tumor growth by cross-linking guanine bases in DNA double-helix strands - directly attacking DNA. This makes the strands unable to uncoil and separate. As this is necessary in DNA replication, the cells can no longer divide. In addition, these drugs add methyl or other alkyl groups onto molecules where they do not belong which in turn inhibits their correct utilization by base pairing and causes a miscoding of DNA. Alkylating agents are cell cycle-nonspecific. Alkylating agents work by three different mechanisms all of which achieve the same end result - disruption of DNA function and cell death.

Chlorbutin Absorption

No information avaliable

Chlorbutin side effects and Toxicity

No information avaliable

Chlorbutin Patient Information

No information avaliable

Chlorbutin Organisms Affected

Humans and other mammals