PharmacyCodes



Phenylbutyric Acid Nitrogen Mustard en es it fr

Phenylbutyric Acid Nitrogen Mustard Brand names, Phenylbutyric Acid Nitrogen Mustard Analogs

Phenylbutyric Acid Nitrogen Mustard Brand Names Mixture

  • No information avaliable

Phenylbutyric Acid Nitrogen Mustard Chemical_Formula

C14H19Cl2NO2

Phenylbutyric Acid Nitrogen Mustard RX_link

http://www.rxlist.com/cgi/generic2/leukeran.htm

Phenylbutyric Acid Nitrogen Mustard fda sheet

Phenylbutyric_Acid_Nitrogen_Mustard FDA

Phenylbutyric Acid Nitrogen Mustard msds (material safety sheet)

Phenylbutyric_Acid_Nitrogen_Mustard MSDS

Phenylbutyric Acid Nitrogen Mustard Synthesis Reference

No information avaliable

Phenylbutyric Acid Nitrogen Mustard Molecular Weight

304.212 g/mol

Phenylbutyric Acid Nitrogen Mustard Melting Point

65 oC

Phenylbutyric Acid Nitrogen Mustard H2O Solubility

1.24E+004 mg/L

Phenylbutyric Acid Nitrogen Mustard State

Solid

Phenylbutyric Acid Nitrogen Mustard LogP

3.25

Phenylbutyric Acid Nitrogen Mustard Dosage Forms

Tablet

Phenylbutyric Acid Nitrogen Mustard Indication

For treatment of chronic lymphatic (lymphocytic) leukemia, malignant lymphomas including lymphosarcoma, giant follicular lymphoma, and Hodgkin's disease

Phenylbutyric Acid Nitrogen Mustard Pharmacology

Chlorambucil is an antineoplastic in the class of alkylating agents and is used to treat various forms of cancer. Alkylating agents are so named because of their ability to add alkyl groups to many electronegative groups under conditions present in cells. They stop tumor growth by cross-linking guanine bases in DNA double-helix strands - directly attacking DNA. This makes the strands unable to uncoil and separate. As this is necessary in DNA replication, the cells can no longer divide. In addition, these drugs add methyl or other alkyl groups onto molecules where they do not belong which in turn inhibits their correct utilization by base pairing and causes a miscoding of DNA. Alkylating agents are cell cycle-nonspecific. Alkylating agents work by three different mechanisms all of which achieve the same end result - disruption of DNA function and cell death.

Phenylbutyric Acid Nitrogen Mustard Absorption

No information avaliable

Phenylbutyric Acid Nitrogen Mustard side effects and Toxicity

No information avaliable

Phenylbutyric Acid Nitrogen Mustard Patient Information

No information avaliable

Phenylbutyric Acid Nitrogen Mustard Organisms Affected

Humans and other mammals