Chloroambucil en es it fr

Chloroambucil Brand names, Chloroambucil Analogs

Chloroambucil Brand Names Mixture

  • No information avaliable

Chloroambucil Chemical_Formula


Chloroambucil RX_link

Chloroambucil fda sheet

Chloroambucil FDA

Chloroambucil msds (material safety sheet)

Chloroambucil MSDS

Chloroambucil Synthesis Reference

No information avaliable

Chloroambucil Molecular Weight

304.212 g/mol

Chloroambucil Melting Point

65 oC

Chloroambucil H2O Solubility

1.24E+004 mg/L

Chloroambucil State


Chloroambucil LogP


Chloroambucil Dosage Forms


Chloroambucil Indication

For treatment of chronic lymphatic (lymphocytic) leukemia, malignant lymphomas including lymphosarcoma, giant follicular lymphoma, and Hodgkin's disease

Chloroambucil Pharmacology

Chlorambucil is an antineoplastic in the class of alkylating agents and is used to treat various forms of cancer. Alkylating agents are so named because of their ability to add alkyl groups to many electronegative groups under conditions present in cells. They stop tumor growth by cross-linking guanine bases in DNA double-helix strands - directly attacking DNA. This makes the strands unable to uncoil and separate. As this is necessary in DNA replication, the cells can no longer divide. In addition, these drugs add methyl or other alkyl groups onto molecules where they do not belong which in turn inhibits their correct utilization by base pairing and causes a miscoding of DNA. Alkylating agents are cell cycle-nonspecific. Alkylating agents work by three different mechanisms all of which achieve the same end result - disruption of DNA function and cell death.

Chloroambucil Absorption

No information avaliable

Chloroambucil side effects and Toxicity

No information avaliable

Chloroambucil Patient Information

No information avaliable

Chloroambucil Organisms Affected

Humans and other mammals