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Elcoril Brand names, Elcoril Analogs

Elcoril Brand Names Mixture

  • No information avaliable

Elcoril Chemical_Formula

C14H19Cl2NO2

Elcoril RX_link

http://www.rxlist.com/cgi/generic2/leukeran.htm

Elcoril fda sheet

Elcoril FDA

Elcoril msds (material safety sheet)

Elcoril MSDS

Elcoril Synthesis Reference

No information avaliable

Elcoril Molecular Weight

304.212 g/mol

Elcoril Melting Point

65 oC

Elcoril H2O Solubility

1.24E+004 mg/L

Elcoril State

Solid

Elcoril LogP

3.25

Elcoril Dosage Forms

Tablet

Elcoril Indication

For treatment of chronic lymphatic (lymphocytic) leukemia, malignant lymphomas including lymphosarcoma, giant follicular lymphoma, and Hodgkin's disease

Elcoril Pharmacology

Chlorambucil is an antineoplastic in the class of alkylating agents and is used to treat various forms of cancer. Alkylating agents are so named because of their ability to add alkyl groups to many electronegative groups under conditions present in cells. They stop tumor growth by cross-linking guanine bases in DNA double-helix strands - directly attacking DNA. This makes the strands unable to uncoil and separate. As this is necessary in DNA replication, the cells can no longer divide. In addition, these drugs add methyl or other alkyl groups onto molecules where they do not belong which in turn inhibits their correct utilization by base pairing and causes a miscoding of DNA. Alkylating agents are cell cycle-nonspecific. Alkylating agents work by three different mechanisms all of which achieve the same end result - disruption of DNA function and cell death.

Elcoril Absorption

No information avaliable

Elcoril side effects and Toxicity

No information avaliable

Elcoril Patient Information

No information avaliable

Elcoril Organisms Affected

Humans and other mammals