Chlorobutin en es it fr

Chlorobutin Brand names, Chlorobutin Analogs

Chlorobutin Brand Names Mixture

  • No information avaliable

Chlorobutin Chemical_Formula


Chlorobutin RX_link

Chlorobutin fda sheet

Chlorobutin FDA

Chlorobutin msds (material safety sheet)

Chlorobutin MSDS

Chlorobutin Synthesis Reference

No information avaliable

Chlorobutin Molecular Weight

304.212 g/mol

Chlorobutin Melting Point

65 oC

Chlorobutin H2O Solubility

1.24E+004 mg/L

Chlorobutin State


Chlorobutin LogP


Chlorobutin Dosage Forms


Chlorobutin Indication

For treatment of chronic lymphatic (lymphocytic) leukemia, malignant lymphomas including lymphosarcoma, giant follicular lymphoma, and Hodgkin's disease

Chlorobutin Pharmacology

Chlorambucil is an antineoplastic in the class of alkylating agents and is used to treat various forms of cancer. Alkylating agents are so named because of their ability to add alkyl groups to many electronegative groups under conditions present in cells. They stop tumor growth by cross-linking guanine bases in DNA double-helix strands - directly attacking DNA. This makes the strands unable to uncoil and separate. As this is necessary in DNA replication, the cells can no longer divide. In addition, these drugs add methyl or other alkyl groups onto molecules where they do not belong which in turn inhibits their correct utilization by base pairing and causes a miscoding of DNA. Alkylating agents are cell cycle-nonspecific. Alkylating agents work by three different mechanisms all of which achieve the same end result - disruption of DNA function and cell death.

Chlorobutin Absorption

No information avaliable

Chlorobutin side effects and Toxicity

No information avaliable

Chlorobutin Patient Information

No information avaliable

Chlorobutin Organisms Affected

Humans and other mammals