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Amboclorin Brand names, Amboclorin Analogs

Amboclorin Brand Names Mixture

  • No information avaliable

Amboclorin Chemical_Formula


Amboclorin RX_link

Amboclorin fda sheet

Amboclorin FDA

Amboclorin msds (material safety sheet)

Amboclorin MSDS

Amboclorin Synthesis Reference

No information avaliable

Amboclorin Molecular Weight

304.212 g/mol

Amboclorin Melting Point

65 oC

Amboclorin H2O Solubility

1.24E+004 mg/L

Amboclorin State


Amboclorin LogP


Amboclorin Dosage Forms


Amboclorin Indication

For treatment of chronic lymphatic (lymphocytic) leukemia, malignant lymphomas including lymphosarcoma, giant follicular lymphoma, and Hodgkin's disease

Amboclorin Pharmacology

Chlorambucil is an antineoplastic in the class of alkylating agents and is used to treat various forms of cancer. Alkylating agents are so named because of their ability to add alkyl groups to many electronegative groups under conditions present in cells. They stop tumor growth by cross-linking guanine bases in DNA double-helix strands - directly attacking DNA. This makes the strands unable to uncoil and separate. As this is necessary in DNA replication, the cells can no longer divide. In addition, these drugs add methyl or other alkyl groups onto molecules where they do not belong which in turn inhibits their correct utilization by base pairing and causes a miscoding of DNA. Alkylating agents are cell cycle-nonspecific. Alkylating agents work by three different mechanisms all of which achieve the same end result - disruption of DNA function and cell death.

Amboclorin Absorption

No information avaliable

Amboclorin side effects and Toxicity

No information avaliable

Amboclorin Patient Information

No information avaliable

Amboclorin Organisms Affected

Humans and other mammals