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Leukeran Brand names, Leukeran Analogs

Leukeran Brand Names Mixture

  • No information avaliable

Leukeran Chemical_Formula


Leukeran RX_link


Leukeran fda sheet

Leukeran FDA

Leukeran msds (material safety sheet)

Leukeran MSDS

Leukeran Synthesis Reference

No information avaliable

Leukeran Molecular Weight

304.212 g/mol

Leukeran Melting Point

65 oC

Leukeran H2O Solubility

1.24E+004 mg/L

Leukeran State


Leukeran LogP


Leukeran Dosage Forms


Leukeran Indication

For treatment of chronic lymphatic (lymphocytic) leukemia, malignant lymphomas including lymphosarcoma, giant follicular lymphoma, and Hodgkin's disease

Leukeran Pharmacology

Chlorambucil is an antineoplastic in the class of alkylating agents and is used to treat various forms of cancer. Alkylating agents are so named because of their ability to add alkyl groups to many electronegative groups under conditions present in cells. They stop tumor growth by cross-linking guanine bases in DNA double-helix strands - directly attacking DNA. This makes the strands unable to uncoil and separate. As this is necessary in DNA replication, the cells can no longer divide. In addition, these drugs add methyl or other alkyl groups onto molecules where they do not belong which in turn inhibits their correct utilization by base pairing and causes a miscoding of DNA. Alkylating agents are cell cycle-nonspecific. Alkylating agents work by three different mechanisms all of which achieve the same end result - disruption of DNA function and cell death.

Leukeran Absorption

No information avaliable

Leukeran side effects and Toxicity

No information avaliable

Leukeran Patient Information

No information avaliable

Leukeran Organisms Affected

Humans and other mammals