Leukeran Tablets en es it fr

Leukeran Tablets Brand names, Leukeran Tablets Analogs

Leukeran Tablets Brand Names Mixture

  • No information avaliable

Leukeran Tablets Chemical_Formula

C14H19Cl2NO2

Leukeran Tablets RX_link

http://www.rxlist.com/cgi/generic2/leukeran.htm

Leukeran Tablets fda sheet

Leukeran_Tablets FDA

Leukeran Tablets msds (material safety sheet)

Leukeran_Tablets MSDS

Leukeran Tablets Synthesis Reference

No information avaliable

Leukeran Tablets Molecular Weight

304.212 g/mol

Leukeran Tablets Melting Point

65 oC

Leukeran Tablets H2O Solubility

1.24E+004 mg/L

Leukeran Tablets State

Solid

Leukeran Tablets LogP

3.25

Leukeran Tablets Dosage Forms

Tablet

Leukeran Tablets Indication

For treatment of chronic lymphatic (lymphocytic) leukemia, malignant lymphomas including lymphosarcoma, giant follicular lymphoma, and Hodgkin's disease

Leukeran Tablets Pharmacology

Chlorambucil is an antineoplastic in the class of alkylating agents and is used to treat various forms of cancer. Alkylating agents are so named because of their ability to add alkyl groups to many electronegative groups under conditions present in cells. They stop tumor growth by cross-linking guanine bases in DNA double-helix strands - directly attacking DNA. This makes the strands unable to uncoil and separate. As this is necessary in DNA replication, the cells can no longer divide. In addition, these drugs add methyl or other alkyl groups onto molecules where they do not belong which in turn inhibits their correct utilization by base pairing and causes a miscoding of DNA. Alkylating agents are cell cycle-nonspecific. Alkylating agents work by three different mechanisms all of which achieve the same end result - disruption of DNA function and cell death.

Leukeran Tablets Absorption

No information avaliable

Leukeran Tablets side effects and Toxicity

No information avaliable

Leukeran Tablets Patient Information

No information avaliable

Leukeran Tablets Organisms Affected

Humans and other mammals