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Brand names,
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Analogs
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Brand Names Mixture
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Chemical_Formula
C13H21NO3
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RX_link
http://www.rxlist.com/cgi/generic/duoneb.htm
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fda sheet
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msds (material safety sheet)
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Synthesis Reference
Collin et al., J. Med. Chem. 3,644,353 (1968,1972)
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Molecular Weight
239.311 g/mol
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Melting Point
157-158oC
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H2O Solubility
3 mg/L
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State
Solid
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LogP
1.311
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Dosage Forms
Oral solution; Syrup; Tablet; Tablet (extended-release); Injection (intramuscular, intravenous)
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Indication
For relief and prevention of bronchospasm due to asthma, emphysema, and chronic bronchitis
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Pharmacology
Albuterol, a moderately selective beta(2)-receptor agonist similar in structure to terbutaline, is widely used as a bronchodilator to manage asthma and other chronic obstructive airway diseases. The R-isomer, levalbuterol, is responsible for bronchodilation while the S-isomer increases bronchial reactivity.
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Absorption
Systemic absorption is rapid following aerosol administration
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side effects and Toxicity
LD50=1100 mg/kg (orally in mice)
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Patient Information
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Organisms Affected
Humans and other mammals