Accuneb
Brand names,
Accuneb
Analogs
Accuneb
Brand Names Mixture
Accuneb
Chemical_Formula
C13H21NO3
Accuneb
RX_link
http://www.rxlist.com/cgi/generic/duoneb.htm
Accuneb
fda sheet
Accuneb
msds (material safety sheet)
Accuneb
Synthesis Reference
Collin et al., J. Med. Chem. 3,644,353 (1968,1972)
Accuneb
Molecular Weight
239.311 g/mol
Accuneb
Melting Point
157-158oC
Accuneb
H2O Solubility
3 mg/L
Accuneb
State
Solid
Accuneb
LogP
1.311
Accuneb
Dosage Forms
Oral solution; Syrup; Tablet; Tablet (extended-release); Injection (intramuscular, intravenous)
Accuneb
Indication
For relief and prevention of bronchospasm due to asthma, emphysema, and chronic bronchitis
Accuneb
Pharmacology
Albuterol, a moderately selective beta(2)-receptor agonist similar in structure to terbutaline, is widely used as a bronchodilator to manage asthma and other chronic obstructive airway diseases. The R-isomer, levalbuterol, is responsible for bronchodilation while the S-isomer increases bronchial reactivity.
Accuneb
Absorption
Systemic absorption is rapid following aerosol administration
Accuneb
side effects and Toxicity
LD50=1100 mg/kg (orally in mice)
Accuneb
Patient Information
Accuneb
Organisms Affected
Humans and other mammals