Loftan
Brand names,
Loftan
Analogs
Loftan
Brand Names Mixture
Loftan
Chemical_Formula
C13H21NO3
Loftan
RX_link
http://www.rxlist.com/cgi/generic/duoneb.htm
Loftan
fda sheet
Loftan
msds (material safety sheet)
Loftan
Synthesis Reference
Collin et al., J. Med. Chem. 3,644,353 (1968,1972)
Loftan
Molecular Weight
239.311 g/mol
Loftan
Melting Point
157-158oC
Loftan
H2O Solubility
3 mg/L
Loftan
State
Solid
Loftan
LogP
1.311
Loftan
Dosage Forms
Oral solution; Syrup; Tablet; Tablet (extended-release); Injection (intramuscular, intravenous)
Loftan
Indication
For relief and prevention of bronchospasm due to asthma, emphysema, and chronic bronchitis
Loftan
Pharmacology
Albuterol, a moderately selective beta(2)-receptor agonist similar in structure to terbutaline, is widely used as a bronchodilator to manage asthma and other chronic obstructive airway diseases. The R-isomer, levalbuterol, is responsible for bronchodilation while the S-isomer increases bronchial reactivity.
Loftan
Absorption
Systemic absorption is rapid following aerosol administration
Loftan
side effects and Toxicity
LD50=1100 mg/kg (orally in mice)
Loftan
Patient Information
Loftan
Organisms Affected
Humans and other mammals