Xopenex HFA
Brand names,
Xopenex HFA
Analogs
Xopenex HFA
Brand Names Mixture
Xopenex HFA
Chemical_Formula
C13H21NO3
Xopenex HFA
RX_link
http://www.rxlist.com/cgi/generic/duoneb.htm
Xopenex HFA
fda sheet
Xopenex HFA
msds (material safety sheet)
Xopenex HFA
Synthesis Reference
Collin et al., J. Med. Chem. 3,644,353 (1968,1972)
Xopenex HFA
Molecular Weight
239.311 g/mol
Xopenex HFA
Melting Point
157-158oC
Xopenex HFA
H2O Solubility
3 mg/L
Xopenex HFA
State
Solid
Xopenex HFA
LogP
1.311
Xopenex HFA
Dosage Forms
Oral solution; Syrup; Tablet; Tablet (extended-release); Injection (intramuscular, intravenous)
Xopenex HFA
Indication
For relief and prevention of bronchospasm due to asthma, emphysema, and chronic bronchitis
Xopenex HFA
Pharmacology
Albuterol, a moderately selective beta(2)-receptor agonist similar in structure to terbutaline, is widely used as a bronchodilator to manage asthma and other chronic obstructive airway diseases. The R-isomer, levalbuterol, is responsible for bronchodilation while the S-isomer increases bronchial reactivity.
Xopenex HFA
Absorption
Systemic absorption is rapid following aerosol administration
Xopenex HFA
side effects and Toxicity
LD50=1100 mg/kg (orally in mice)
Xopenex HFA
Patient Information
Xopenex HFA
Organisms Affected
Humans and other mammals