Salbuvent
Brand names,
Salbuvent
Analogs
Salbuvent
Brand Names Mixture
Salbuvent
Chemical_Formula
C13H21NO3
Salbuvent
RX_link
http://www.rxlist.com/cgi/generic/duoneb.htm
Salbuvent
fda sheet
Salbuvent
msds (material safety sheet)
Salbuvent
Synthesis Reference
Collin et al., J. Med. Chem. 3,644,353 (1968,1972)
Salbuvent
Molecular Weight
239.311 g/mol
Salbuvent
Melting Point
157-158oC
Salbuvent
H2O Solubility
3 mg/L
Salbuvent
State
Solid
Salbuvent
LogP
1.311
Salbuvent
Dosage Forms
Oral solution; Syrup; Tablet; Tablet (extended-release); Injection (intramuscular, intravenous)
Salbuvent
Indication
For relief and prevention of bronchospasm due to asthma, emphysema, and chronic bronchitis
Salbuvent
Pharmacology
Albuterol, a moderately selective beta(2)-receptor agonist similar in structure to terbutaline, is widely used as a bronchodilator to manage asthma and other chronic obstructive airway diseases. The R-isomer, levalbuterol, is responsible for bronchodilation while the S-isomer increases bronchial reactivity.
Salbuvent
Absorption
Systemic absorption is rapid following aerosol administration
Salbuvent
side effects and Toxicity
LD50=1100 mg/kg (orally in mice)
Salbuvent
Patient Information
Salbuvent
Organisms Affected
Humans and other mammals