Cobutolin

Cobutolin Brand names, Cobutolin Analogs

Cobutolin Brand Names Mixture

Aerolin (Sulfate)

Cobutolin Chemical_Formula

C₁₃H₂₁NO₃

Cobutolin RX_link

http://www.rxlist.com/cgi/generic/duoneb.htm

Cobutolin fda sheet

Cobutolin FDA

Cobutolin msds (material safety sheet)

Cobutolin MSDS

Cobutolin Synthesis Reference

Collin et al., J. Med. Chem. 3,644,353 (1968,1972)

Cobutolin Molecular Weight

239.311 g/mol

Cobutolin Melting Point

157-158^oC

Cobutolin H₂O Solubility

3 mg/L

Cobutolin State

Solid

Cobutolin LogP

1.311

Cobutolin Dosage Forms

Oral solution; Syrup; Tablet; Tablet (extended-release); Injection (intramuscular, intravenous)

Cobutolin Indication

For relief and prevention of bronchospasm due to asthma, emphysema, and chronic bronchitis

Cobutolin Pharmacology

Albuterol, a moderately selective beta(2)-receptor agonist similar in structure to terbutaline, is widely used as a bronchodilator to manage asthma and other chronic obstructive airway diseases. The R-isomer, levalbuterol, is responsible for bronchodilation while the S-isomer increases bronchial reactivity.

Cobutolin Absorption

Systemic absorption is rapid following aerosol administration

Cobutolin side effects and Toxicity

LD₅₀=1100 mg/kg (orally in mice)

Cobutolin Patient Information

Cobutolin Organisms Affected

Humans and other mammals