Albuterol Sulfate Hfa
Brand names,
Albuterol Sulfate Hfa
Analogs
Albuterol Sulfate Hfa
Brand Names Mixture
Albuterol Sulfate Hfa
Chemical_Formula
C13H21NO3
Albuterol Sulfate Hfa
RX_link
http://www.rxlist.com/cgi/generic/duoneb.htm
Albuterol Sulfate Hfa
fda sheet
Albuterol Sulfate Hfa
msds (material safety sheet)
Albuterol Sulfate Hfa
Synthesis Reference
Collin et al., J. Med. Chem. 3,644,353 (1968,1972)
Albuterol Sulfate Hfa
Molecular Weight
239.311 g/mol
Albuterol Sulfate Hfa
Melting Point
157-158oC
Albuterol Sulfate Hfa
H2O Solubility
3 mg/L
Albuterol Sulfate Hfa
State
Solid
Albuterol Sulfate Hfa
LogP
1.311
Albuterol Sulfate Hfa
Dosage Forms
Oral solution; Syrup; Tablet; Tablet (extended-release); Injection (intramuscular, intravenous)
Albuterol Sulfate Hfa
Indication
For relief and prevention of bronchospasm due to asthma, emphysema, and chronic bronchitis
Albuterol Sulfate Hfa
Pharmacology
Albuterol, a moderately selective beta(2)-receptor agonist similar in structure to terbutaline, is widely used as a bronchodilator to manage asthma and other chronic obstructive airway diseases. The R-isomer, levalbuterol, is responsible for bronchodilation while the S-isomer increases bronchial reactivity.
Albuterol Sulfate Hfa
Absorption
Systemic absorption is rapid following aerosol administration
Albuterol Sulfate Hfa
side effects and Toxicity
LD50=1100 mg/kg (orally in mice)
Albuterol Sulfate Hfa
Patient Information
Albuterol Sulfate Hfa
Organisms Affected
Humans and other mammals