Salbutamol Free Base
Brand names,
Salbutamol Free Base
Analogs
Salbutamol Free Base
Brand Names Mixture
Salbutamol Free Base
Chemical_Formula
C13H21NO3
Salbutamol Free Base
RX_link
http://www.rxlist.com/cgi/generic/duoneb.htm
Salbutamol Free Base
fda sheet
Salbutamol Free Base
msds (material safety sheet)
Salbutamol Free Base
Synthesis Reference
Collin et al., J. Med. Chem. 3,644,353 (1968,1972)
Salbutamol Free Base
Molecular Weight
239.311 g/mol
Salbutamol Free Base
Melting Point
157-158oC
Salbutamol Free Base
H2O Solubility
3 mg/L
Salbutamol Free Base
State
Solid
Salbutamol Free Base
LogP
1.311
Salbutamol Free Base
Dosage Forms
Oral solution; Syrup; Tablet; Tablet (extended-release); Injection (intramuscular, intravenous)
Salbutamol Free Base
Indication
For relief and prevention of bronchospasm due to asthma, emphysema, and chronic bronchitis
Salbutamol Free Base
Pharmacology
Albuterol, a moderately selective beta(2)-receptor agonist similar in structure to terbutaline, is widely used as a bronchodilator to manage asthma and other chronic obstructive airway diseases. The R-isomer, levalbuterol, is responsible for bronchodilation while the S-isomer increases bronchial reactivity.
Salbutamol Free Base
Absorption
Systemic absorption is rapid following aerosol administration
Salbutamol Free Base
side effects and Toxicity
LD50=1100 mg/kg (orally in mice)
Salbutamol Free Base
Patient Information
Salbutamol Free Base
Organisms Affected
Humans and other mammals