Salbutamol
Brand names,
Salbutamol
Analogs
Salbutamol
Brand Names Mixture
Salbutamol
Chemical_Formula
C13H21NO3
Salbutamol
RX_link
http://www.rxlist.com/cgi/generic/duoneb.htm
Salbutamol
fda sheet
Salbutamol
msds (material safety sheet)
Salbutamol
Synthesis Reference
Collin et al., J. Med. Chem. 3,644,353 (1968,1972)
Salbutamol
Molecular Weight
239.311 g/mol
Salbutamol
Melting Point
157-158oC
Salbutamol
H2O Solubility
3 mg/L
Salbutamol
State
Solid
Salbutamol
LogP
1.311
Salbutamol
Dosage Forms
Oral solution; Syrup; Tablet; Tablet (extended-release); Injection (intramuscular, intravenous)
Salbutamol
Indication
For relief and prevention of bronchospasm due to asthma, emphysema, and chronic bronchitis
Salbutamol
Pharmacology
Albuterol, a moderately selective beta(2)-receptor agonist similar in structure to terbutaline, is widely used as a bronchodilator to manage asthma and other chronic obstructive airway diseases. The R-isomer, levalbuterol, is responsible for bronchodilation while the S-isomer increases bronchial reactivity.
Salbutamol
Absorption
Systemic absorption is rapid following aerosol administration
Salbutamol
side effects and Toxicity
LD50=1100 mg/kg (orally in mice)
Salbutamol
Patient Information
Salbutamol
Organisms Affected
Humans and other mammals