Solbutamol
Brand names,
Solbutamol
Analogs
Solbutamol
Brand Names Mixture
Solbutamol
Chemical_Formula
C13H21NO3
Solbutamol
RX_link
http://www.rxlist.com/cgi/generic/duoneb.htm
Solbutamol
fda sheet
Solbutamol
msds (material safety sheet)
Solbutamol
Synthesis Reference
Collin et al., J. Med. Chem. 3,644,353 (1968,1972)
Solbutamol
Molecular Weight
239.311 g/mol
Solbutamol
Melting Point
157-158oC
Solbutamol
H2O Solubility
3 mg/L
Solbutamol
State
Solid
Solbutamol
LogP
1.311
Solbutamol
Dosage Forms
Oral solution; Syrup; Tablet; Tablet (extended-release); Injection (intramuscular, intravenous)
Solbutamol
Indication
For relief and prevention of bronchospasm due to asthma, emphysema, and chronic bronchitis
Solbutamol
Pharmacology
Albuterol, a moderately selective beta(2)-receptor agonist similar in structure to terbutaline, is widely used as a bronchodilator to manage asthma and other chronic obstructive airway diseases. The R-isomer, levalbuterol, is responsible for bronchodilation while the S-isomer increases bronchial reactivity.
Solbutamol
Absorption
Systemic absorption is rapid following aerosol administration
Solbutamol
side effects and Toxicity
LD50=1100 mg/kg (orally in mice)
Solbutamol
Patient Information
Solbutamol
Organisms Affected
Humans and other mammals