Albuterol Sulfate
Brand names,
Albuterol Sulfate
Analogs
Albuterol Sulfate
Brand Names Mixture
Albuterol Sulfate
Chemical_Formula
C13H21NO3
Albuterol Sulfate
RX_link
http://www.rxlist.com/cgi/generic/duoneb.htm
Albuterol Sulfate
fda sheet
Albuterol Sulfate
msds (material safety sheet)
Albuterol Sulfate
Synthesis Reference
Collin et al., J. Med. Chem. 3,644,353 (1968,1972)
Albuterol Sulfate
Molecular Weight
239.311 g/mol
Albuterol Sulfate
Melting Point
157-158oC
Albuterol Sulfate
H2O Solubility
3 mg/L
Albuterol Sulfate
State
Solid
Albuterol Sulfate
LogP
1.311
Albuterol Sulfate
Dosage Forms
Oral solution; Syrup; Tablet; Tablet (extended-release); Injection (intramuscular, intravenous)
Albuterol Sulfate
Indication
For relief and prevention of bronchospasm due to asthma, emphysema, and chronic bronchitis
Albuterol Sulfate
Pharmacology
Albuterol, a moderately selective beta(2)-receptor agonist similar in structure to terbutaline, is widely used as a bronchodilator to manage asthma and other chronic obstructive airway diseases. The R-isomer, levalbuterol, is responsible for bronchodilation while the S-isomer increases bronchial reactivity.
Albuterol Sulfate
Absorption
Systemic absorption is rapid following aerosol administration
Albuterol Sulfate
side effects and Toxicity
LD50=1100 mg/kg (orally in mice)
Albuterol Sulfate
Patient Information
Albuterol Sulfate
Organisms Affected
Humans and other mammals