Proventil-Hfa
Brand names,
Proventil-Hfa
Analogs
Proventil-Hfa
Brand Names Mixture
Proventil-Hfa
Chemical_Formula
C13H21NO3
Proventil-Hfa
RX_link
http://www.rxlist.com/cgi/generic/duoneb.htm
Proventil-Hfa
fda sheet
Proventil-Hfa
msds (material safety sheet)
Proventil-Hfa
Synthesis Reference
Collin et al., J. Med. Chem. 3,644,353 (1968,1972)
Proventil-Hfa
Molecular Weight
239.311 g/mol
Proventil-Hfa
Melting Point
157-158oC
Proventil-Hfa
H2O Solubility
3 mg/L
Proventil-Hfa
State
Solid
Proventil-Hfa
LogP
1.311
Proventil-Hfa
Dosage Forms
Oral solution; Syrup; Tablet; Tablet (extended-release); Injection (intramuscular, intravenous)
Proventil-Hfa
Indication
For relief and prevention of bronchospasm due to asthma, emphysema, and chronic bronchitis
Proventil-Hfa
Pharmacology
Albuterol, a moderately selective beta(2)-receptor agonist similar in structure to terbutaline, is widely used as a bronchodilator to manage asthma and other chronic obstructive airway diseases. The R-isomer, levalbuterol, is responsible for bronchodilation while the S-isomer increases bronchial reactivity.
Proventil-Hfa
Absorption
Systemic absorption is rapid following aerosol administration
Proventil-Hfa
side effects and Toxicity
LD50=1100 mg/kg (orally in mice)
Proventil-Hfa
Patient Information
Proventil-Hfa
Organisms Affected
Humans and other mammals