Salbutamol Sulphate
Brand names,
Salbutamol Sulphate
Analogs
Salbutamol Sulphate
Brand Names Mixture
Salbutamol Sulphate
Chemical_Formula
C13H21NO3
Salbutamol Sulphate
RX_link
http://www.rxlist.com/cgi/generic/duoneb.htm
Salbutamol Sulphate
fda sheet
Salbutamol Sulphate
msds (material safety sheet)
Salbutamol Sulphate
Synthesis Reference
Collin et al., J. Med. Chem. 3,644,353 (1968,1972)
Salbutamol Sulphate
Molecular Weight
239.311 g/mol
Salbutamol Sulphate
Melting Point
157-158oC
Salbutamol Sulphate
H2O Solubility
3 mg/L
Salbutamol Sulphate
State
Solid
Salbutamol Sulphate
LogP
1.311
Salbutamol Sulphate
Dosage Forms
Oral solution; Syrup; Tablet; Tablet (extended-release); Injection (intramuscular, intravenous)
Salbutamol Sulphate
Indication
For relief and prevention of bronchospasm due to asthma, emphysema, and chronic bronchitis
Salbutamol Sulphate
Pharmacology
Albuterol, a moderately selective beta(2)-receptor agonist similar in structure to terbutaline, is widely used as a bronchodilator to manage asthma and other chronic obstructive airway diseases. The R-isomer, levalbuterol, is responsible for bronchodilation while the S-isomer increases bronchial reactivity.
Salbutamol Sulphate
Absorption
Systemic absorption is rapid following aerosol administration
Salbutamol Sulphate
side effects and Toxicity
LD50=1100 mg/kg (orally in mice)
Salbutamol Sulphate
Patient Information
Salbutamol Sulphate
Organisms Affected
Humans and other mammals