Salbutamol Sulfate
Brand names,
Salbutamol Sulfate
Analogs
Salbutamol Sulfate
Brand Names Mixture
Salbutamol Sulfate
Chemical_Formula
C13H21NO3
Salbutamol Sulfate
RX_link
http://www.rxlist.com/cgi/generic/duoneb.htm
Salbutamol Sulfate
fda sheet
Salbutamol Sulfate
msds (material safety sheet)
Salbutamol Sulfate
Synthesis Reference
Collin et al., J. Med. Chem. 3,644,353 (1968,1972)
Salbutamol Sulfate
Molecular Weight
239.311 g/mol
Salbutamol Sulfate
Melting Point
157-158oC
Salbutamol Sulfate
H2O Solubility
3 mg/L
Salbutamol Sulfate
State
Solid
Salbutamol Sulfate
LogP
1.311
Salbutamol Sulfate
Dosage Forms
Oral solution; Syrup; Tablet; Tablet (extended-release); Injection (intramuscular, intravenous)
Salbutamol Sulfate
Indication
For relief and prevention of bronchospasm due to asthma, emphysema, and chronic bronchitis
Salbutamol Sulfate
Pharmacology
Albuterol, a moderately selective beta(2)-receptor agonist similar in structure to terbutaline, is widely used as a bronchodilator to manage asthma and other chronic obstructive airway diseases. The R-isomer, levalbuterol, is responsible for bronchodilation while the S-isomer increases bronchial reactivity.
Salbutamol Sulfate
Absorption
Systemic absorption is rapid following aerosol administration
Salbutamol Sulfate
side effects and Toxicity
LD50=1100 mg/kg (orally in mice)
Salbutamol Sulfate
Patient Information
Salbutamol Sulfate
Organisms Affected
Humans and other mammals