Dicumarol
Brand names,
Dicumarol
Analogs
Dicumarol
Brand Names Mixture
Dicumarol
Chemical_Formula
C19H12O6
Dicumarol
RX_link
No information avaliable
Dicumarol
fda sheet
Dicumarol
msds (material safety sheet)
Dicumarol
Synthesis Reference
Bikova N., et al. Farmatsiia (Sofia). 1954 Jan-Feb;4(1):23-6.
Dicumarol
Molecular Weight
336.295 g/mol
Dicumarol
Melting Point
290 oC
Dicumarol
H2O Solubility
128 mg/L
Dicumarol
State
Solid
Dicumarol
LogP
3.447
Dicumarol
Dosage Forms
No information avaliable
Dicumarol
Indication
For decreasing blood clotting
Dicumarol
Pharmacology
Dicumarol is an coumarin-like compound found in sweet clover. It is used as an oral anticoagulant and acts by inhibiting the hepatic synthesis of vitamin K-dependent coagulation factors (prothrombin and factors VII, IX, and X). It is also used in biochemical experiments as an inhibitor of reductases.
Dicumarol
Absorption
No information avaliable
Dicumarol
side effects and Toxicity
LD50=233 mg/kg (orally in mice); LD50=250 mg/kg (orally in rats)
Dicumarol
Patient Information
No information avaliable
Dicumarol
Organisms Affected
Humans and other mammals