Antitrombosin
Brand names,
Antitrombosin
Analogs
Antitrombosin
Brand Names Mixture
Antitrombosin
Chemical_Formula
C19H12O6
Antitrombosin
RX_link
No information avaliable
Antitrombosin
fda sheet
Antitrombosin
msds (material safety sheet)
Antitrombosin
Synthesis Reference
Bikova N., et al. Farmatsiia (Sofia). 1954 Jan-Feb;4(1):23-6.
Antitrombosin
Molecular Weight
336.295 g/mol
Antitrombosin
Melting Point
290 oC
Antitrombosin
H2O Solubility
128 mg/L
Antitrombosin
State
Solid
Antitrombosin
LogP
3.447
Antitrombosin
Dosage Forms
No information avaliable
Antitrombosin
Indication
For decreasing blood clotting
Antitrombosin
Pharmacology
Dicumarol is an coumarin-like compound found in sweet clover. It is used as an oral anticoagulant and acts by inhibiting the hepatic synthesis of vitamin K-dependent coagulation factors (prothrombin and factors VII, IX, and X). It is also used in biochemical experiments as an inhibitor of reductases.
Antitrombosin
Absorption
No information avaliable
Antitrombosin
side effects and Toxicity
LD50=233 mg/kg (orally in mice); LD50=250 mg/kg (orally in rats)
Antitrombosin
Patient Information
No information avaliable
Antitrombosin
Organisms Affected
Humans and other mammals