Cuma
Brand names,
Cuma
Analogs
Cuma
Brand Names Mixture
Cuma
Chemical_Formula
C19H12O6
Cuma
RX_link
No information avaliable
Cuma
fda sheet
Cuma
msds (material safety sheet)
Cuma
Synthesis Reference
Bikova N., et al. Farmatsiia (Sofia). 1954 Jan-Feb;4(1):23-6.
Cuma
Molecular Weight
336.295 g/mol
Cuma
Melting Point
290 oC
Cuma
H2O Solubility
128 mg/L
Cuma
State
Solid
Cuma
LogP
3.447
Cuma
Dosage Forms
No information avaliable
Cuma
Indication
For decreasing blood clotting
Cuma
Pharmacology
Dicumarol is an coumarin-like compound found in sweet clover. It is used as an oral anticoagulant and acts by inhibiting the hepatic synthesis of vitamin K-dependent coagulation factors (prothrombin and factors VII, IX, and X). It is also used in biochemical experiments as an inhibitor of reductases.
Cuma
Absorption
No information avaliable
Cuma
side effects and Toxicity
LD50=233 mg/kg (orally in mice); LD50=250 mg/kg (orally in rats)
Cuma
Patient Information
No information avaliable
Cuma
Organisms Affected
Humans and other mammals