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Brand names,
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Analogs
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Brand Names Mixture
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Chemical_Formula
C19H12O6
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RX_link
No information avaliable
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fda sheet
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msds (material safety sheet)
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Synthesis Reference
Bikova N., et al. Farmatsiia (Sofia). 1954 Jan-Feb;4(1):23-6.
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Molecular Weight
336.295 g/mol
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Melting Point
290 oC
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H2O Solubility
128 mg/L
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State
Solid
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LogP
3.447
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Dosage Forms
No information avaliable
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Indication
For decreasing blood clotting
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Pharmacology
Dicumarol is an coumarin-like compound found in sweet clover. It is used as an oral anticoagulant and acts by inhibiting the hepatic synthesis of vitamin K-dependent coagulation factors (prothrombin and factors VII, IX, and X). It is also used in biochemical experiments as an inhibitor of reductases.
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Absorption
No information avaliable
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side effects and Toxicity
LD50=233 mg/kg (orally in mice); LD50=250 mg/kg (orally in rats)
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Patient Information
No information avaliable
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Organisms Affected
Humans and other mammals