Dicoumal
Dicoumal Brand names, Dicoumal Analogs
Dicoumal Brand Names Mixture
- No information avaliable
Dicoumal Chemical_Formula
C19H12O6
Dicoumal RX_link
No information avaliable
Dicoumal fda sheet
Dicoumal msds (material safety sheet)
Dicoumal Synthesis Reference
Bikova N., et al. Farmatsiia (Sofia). 1954 Jan-Feb;4(1):23-6.
Dicoumal Molecular Weight
336.295 g/mol
Dicoumal Melting Point
290 oC
Dicoumal H2O Solubility
128 mg/L
Dicoumal State
Solid
Dicoumal LogP
3.447
Dicoumal Dosage Forms
No information avaliable
Dicoumal Indication
For decreasing blood clotting
Dicoumal Pharmacology
Dicumarol is an coumarin-like compound found in sweet clover. It is used as an oral anticoagulant and acts by inhibiting the hepatic synthesis of vitamin K-dependent coagulation factors (prothrombin and factors VII, IX, and X). It is also used in biochemical experiments as an inhibitor of reductases.
Dicoumal Absorption
No information avaliable
Dicoumal side effects and Toxicity
LD50=233 mg/kg (orally in mice); LD50=250 mg/kg (orally in rats)
Dicoumal Patient Information
No information avaliable
Dicoumal Organisms Affected
Humans and other mammals
