Dicumaol R
Brand names,
Dicumaol R
Analogs
Dicumaol R
Brand Names Mixture
Dicumaol R
Chemical_Formula
C19H12O6
Dicumaol R
RX_link
No information avaliable
Dicumaol R
fda sheet
Dicumaol R
msds (material safety sheet)
Dicumaol R
Synthesis Reference
Bikova N., et al. Farmatsiia (Sofia). 1954 Jan-Feb;4(1):23-6.
Dicumaol R
Molecular Weight
336.295 g/mol
Dicumaol R
Melting Point
290 oC
Dicumaol R
H2O Solubility
128 mg/L
Dicumaol R
State
Solid
Dicumaol R
LogP
3.447
Dicumaol R
Dosage Forms
No information avaliable
Dicumaol R
Indication
For decreasing blood clotting
Dicumaol R
Pharmacology
Dicumarol is an coumarin-like compound found in sweet clover. It is used as an oral anticoagulant and acts by inhibiting the hepatic synthesis of vitamin K-dependent coagulation factors (prothrombin and factors VII, IX, and X). It is also used in biochemical experiments as an inhibitor of reductases.
Dicumaol R
Absorption
No information avaliable
Dicumaol R
side effects and Toxicity
LD50=233 mg/kg (orally in mice); LD50=250 mg/kg (orally in rats)
Dicumaol R
Patient Information
No information avaliable
Dicumaol R
Organisms Affected
Humans and other mammals