Temparin
Brand names,
Temparin
Analogs
Temparin
Brand Names Mixture
Temparin
Chemical_Formula
C19H12O6
Temparin
RX_link
No information avaliable
Temparin
fda sheet
Temparin
msds (material safety sheet)
Temparin
Synthesis Reference
Bikova N., et al. Farmatsiia (Sofia). 1954 Jan-Feb;4(1):23-6.
Temparin
Molecular Weight
336.295 g/mol
Temparin
Melting Point
290 oC
Temparin
H2O Solubility
128 mg/L
Temparin
State
Solid
Temparin
LogP
3.447
Temparin
Dosage Forms
No information avaliable
Temparin
Indication
For decreasing blood clotting
Temparin
Pharmacology
Dicumarol is an coumarin-like compound found in sweet clover. It is used as an oral anticoagulant and acts by inhibiting the hepatic synthesis of vitamin K-dependent coagulation factors (prothrombin and factors VII, IX, and X). It is also used in biochemical experiments as an inhibitor of reductases.
Temparin
Absorption
No information avaliable
Temparin
side effects and Toxicity
LD50=233 mg/kg (orally in mice); LD50=250 mg/kg (orally in rats)
Temparin
Patient Information
No information avaliable
Temparin
Organisms Affected
Humans and other mammals