Dufalone
Brand names,
Dufalone
Analogs
Dufalone
Brand Names Mixture
Dufalone
Chemical_Formula
C19H12O6
Dufalone
RX_link
No information avaliable
Dufalone
fda sheet
Dufalone
msds (material safety sheet)
Dufalone
Synthesis Reference
Bikova N., et al. Farmatsiia (Sofia). 1954 Jan-Feb;4(1):23-6.
Dufalone
Molecular Weight
336.295 g/mol
Dufalone
Melting Point
290 oC
Dufalone
H2O Solubility
128 mg/L
Dufalone
State
Solid
Dufalone
LogP
3.447
Dufalone
Dosage Forms
No information avaliable
Dufalone
Indication
For decreasing blood clotting
Dufalone
Pharmacology
Dicumarol is an coumarin-like compound found in sweet clover. It is used as an oral anticoagulant and acts by inhibiting the hepatic synthesis of vitamin K-dependent coagulation factors (prothrombin and factors VII, IX, and X). It is also used in biochemical experiments as an inhibitor of reductases.
Dufalone
Absorption
No information avaliable
Dufalone
side effects and Toxicity
LD50=233 mg/kg (orally in mice); LD50=250 mg/kg (orally in rats)
Dufalone
Patient Information
No information avaliable
Dufalone
Organisms Affected
Humans and other mammals