Dicumol
Brand names,
Dicumol
Analogs
Dicumol
Brand Names Mixture
Dicumol
Chemical_Formula
C19H12O6
Dicumol
RX_link
No information avaliable
Dicumol
fda sheet
Dicumol
msds (material safety sheet)
Dicumol
Synthesis Reference
Bikova N., et al. Farmatsiia (Sofia). 1954 Jan-Feb;4(1):23-6.
Dicumol
Molecular Weight
336.295 g/mol
Dicumol
Melting Point
290 oC
Dicumol
H2O Solubility
128 mg/L
Dicumol
State
Solid
Dicumol
LogP
3.447
Dicumol
Dosage Forms
No information avaliable
Dicumol
Indication
For decreasing blood clotting
Dicumol
Pharmacology
Dicumarol is an coumarin-like compound found in sweet clover. It is used as an oral anticoagulant and acts by inhibiting the hepatic synthesis of vitamin K-dependent coagulation factors (prothrombin and factors VII, IX, and X). It is also used in biochemical experiments as an inhibitor of reductases.
Dicumol
Absorption
No information avaliable
Dicumol
side effects and Toxicity
LD50=233 mg/kg (orally in mice); LD50=250 mg/kg (orally in rats)
Dicumol
Patient Information
No information avaliable
Dicumol
Organisms Affected
Humans and other mammals