Bis-Hydroxycoumarin
Brand names,
Bis-Hydroxycoumarin
Analogs
Bis-Hydroxycoumarin
Brand Names Mixture
Bis-Hydroxycoumarin
Chemical_Formula
C19H12O6
Bis-Hydroxycoumarin
RX_link
No information avaliable
Bis-Hydroxycoumarin
fda sheet
Bis-Hydroxycoumarin
msds (material safety sheet)
Bis-Hydroxycoumarin
Synthesis Reference
Bikova N., et al. Farmatsiia (Sofia). 1954 Jan-Feb;4(1):23-6.
Bis-Hydroxycoumarin
Molecular Weight
336.295 g/mol
Bis-Hydroxycoumarin
Melting Point
290 oC
Bis-Hydroxycoumarin
H2O Solubility
128 mg/L
Bis-Hydroxycoumarin
State
Solid
Bis-Hydroxycoumarin
LogP
3.447
Bis-Hydroxycoumarin
Dosage Forms
No information avaliable
Bis-Hydroxycoumarin
Indication
For decreasing blood clotting
Bis-Hydroxycoumarin
Pharmacology
Dicumarol is an coumarin-like compound found in sweet clover. It is used as an oral anticoagulant and acts by inhibiting the hepatic synthesis of vitamin K-dependent coagulation factors (prothrombin and factors VII, IX, and X). It is also used in biochemical experiments as an inhibitor of reductases.
Bis-Hydroxycoumarin
Absorption
No information avaliable
Bis-Hydroxycoumarin
side effects and Toxicity
LD50=233 mg/kg (orally in mice); LD50=250 mg/kg (orally in rats)
Bis-Hydroxycoumarin
Patient Information
No information avaliable
Bis-Hydroxycoumarin
Organisms Affected
Humans and other mammals