Dicoumarin
Brand names,
Dicoumarin
Analogs
Dicoumarin
Brand Names Mixture
Dicoumarin
Chemical_Formula
C19H12O6
Dicoumarin
RX_link
No information avaliable
Dicoumarin
fda sheet
Dicoumarin
msds (material safety sheet)
Dicoumarin
Synthesis Reference
Bikova N., et al. Farmatsiia (Sofia). 1954 Jan-Feb;4(1):23-6.
Dicoumarin
Molecular Weight
336.295 g/mol
Dicoumarin
Melting Point
290 oC
Dicoumarin
H2O Solubility
128 mg/L
Dicoumarin
State
Solid
Dicoumarin
LogP
3.447
Dicoumarin
Dosage Forms
No information avaliable
Dicoumarin
Indication
For decreasing blood clotting
Dicoumarin
Pharmacology
Dicumarol is an coumarin-like compound found in sweet clover. It is used as an oral anticoagulant and acts by inhibiting the hepatic synthesis of vitamin K-dependent coagulation factors (prothrombin and factors VII, IX, and X). It is also used in biochemical experiments as an inhibitor of reductases.
Dicoumarin
Absorption
No information avaliable
Dicoumarin
side effects and Toxicity
LD50=233 mg/kg (orally in mice); LD50=250 mg/kg (orally in rats)
Dicoumarin
Patient Information
No information avaliable
Dicoumarin
Organisms Affected
Humans and other mammals