Dikumarol
Brand names,
Dikumarol
Analogs
Dikumarol
Brand Names Mixture
Dikumarol
Chemical_Formula
C19H12O6
Dikumarol
RX_link
No information avaliable
Dikumarol
fda sheet
Dikumarol
msds (material safety sheet)
Dikumarol
Synthesis Reference
Bikova N., et al. Farmatsiia (Sofia). 1954 Jan-Feb;4(1):23-6.
Dikumarol
Molecular Weight
336.295 g/mol
Dikumarol
Melting Point
290 oC
Dikumarol
H2O Solubility
128 mg/L
Dikumarol
State
Solid
Dikumarol
LogP
3.447
Dikumarol
Dosage Forms
No information avaliable
Dikumarol
Indication
For decreasing blood clotting
Dikumarol
Pharmacology
Dicumarol is an coumarin-like compound found in sweet clover. It is used as an oral anticoagulant and acts by inhibiting the hepatic synthesis of vitamin K-dependent coagulation factors (prothrombin and factors VII, IX, and X). It is also used in biochemical experiments as an inhibitor of reductases.
Dikumarol
Absorption
No information avaliable
Dikumarol
side effects and Toxicity
LD50=233 mg/kg (orally in mice); LD50=250 mg/kg (orally in rats)
Dikumarol
Patient Information
No information avaliable
Dikumarol
Organisms Affected
Humans and other mammals