Dicuman
Brand names,
Dicuman
Analogs
Dicuman
Brand Names Mixture
Dicuman
Chemical_Formula
C19H12O6
Dicuman
RX_link
No information avaliable
Dicuman
fda sheet
Dicuman
msds (material safety sheet)
Dicuman
Synthesis Reference
Bikova N., et al. Farmatsiia (Sofia). 1954 Jan-Feb;4(1):23-6.
Dicuman
Molecular Weight
336.295 g/mol
Dicuman
Melting Point
290 oC
Dicuman
H2O Solubility
128 mg/L
Dicuman
State
Solid
Dicuman
LogP
3.447
Dicuman
Dosage Forms
No information avaliable
Dicuman
Indication
For decreasing blood clotting
Dicuman
Pharmacology
Dicumarol is an coumarin-like compound found in sweet clover. It is used as an oral anticoagulant and acts by inhibiting the hepatic synthesis of vitamin K-dependent coagulation factors (prothrombin and factors VII, IX, and X). It is also used in biochemical experiments as an inhibitor of reductases.
Dicuman
Absorption
No information avaliable
Dicuman
side effects and Toxicity
LD50=233 mg/kg (orally in mice); LD50=250 mg/kg (orally in rats)
Dicuman
Patient Information
No information avaliable
Dicuman
Organisms Affected
Humans and other mammals