Dicoumarol
Brand names,
Dicoumarol
Analogs
Dicoumarol
Brand Names Mixture
Dicoumarol
Chemical_Formula
C19H12O6
Dicoumarol
RX_link
No information avaliable
Dicoumarol
fda sheet
Dicoumarol
msds (material safety sheet)
Dicoumarol
Synthesis Reference
Bikova N., et al. Farmatsiia (Sofia). 1954 Jan-Feb;4(1):23-6.
Dicoumarol
Molecular Weight
336.295 g/mol
Dicoumarol
Melting Point
290 oC
Dicoumarol
H2O Solubility
128 mg/L
Dicoumarol
State
Solid
Dicoumarol
LogP
3.447
Dicoumarol
Dosage Forms
No information avaliable
Dicoumarol
Indication
For decreasing blood clotting
Dicoumarol
Pharmacology
Dicumarol is an coumarin-like compound found in sweet clover. It is used as an oral anticoagulant and acts by inhibiting the hepatic synthesis of vitamin K-dependent coagulation factors (prothrombin and factors VII, IX, and X). It is also used in biochemical experiments as an inhibitor of reductases.
Dicoumarol
Absorption
No information avaliable
Dicoumarol
side effects and Toxicity
LD50=233 mg/kg (orally in mice); LD50=250 mg/kg (orally in rats)
Dicoumarol
Patient Information
No information avaliable
Dicoumarol
Organisms Affected
Humans and other mammals