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Chlorambucil Brand names, Chlorambucil Analogs

Chlorambucil Brand Names Mixture

  • No information avaliable

Chlorambucil Chemical_Formula


Chlorambucil RX_link

Chlorambucil fda sheet

Chlorambucil FDA

Chlorambucil msds (material safety sheet)

Chlorambucil MSDS

Chlorambucil Synthesis Reference

No information avaliable

Chlorambucil Molecular Weight

304.212 g/mol

Chlorambucil Melting Point

65 oC

Chlorambucil H2O Solubility

1.24E+004 mg/L

Chlorambucil State


Chlorambucil LogP


Chlorambucil Dosage Forms


Chlorambucil Indication

For treatment of chronic lymphatic (lymphocytic) leukemia, malignant lymphomas including lymphosarcoma, giant follicular lymphoma, and Hodgkin's disease

Chlorambucil Pharmacology

Chlorambucil is an antineoplastic in the class of alkylating agents and is used to treat various forms of cancer. Alkylating agents are so named because of their ability to add alkyl groups to many electronegative groups under conditions present in cells. They stop tumor growth by cross-linking guanine bases in DNA double-helix strands - directly attacking DNA. This makes the strands unable to uncoil and separate. As this is necessary in DNA replication, the cells can no longer divide. In addition, these drugs add methyl or other alkyl groups onto molecules where they do not belong which in turn inhibits their correct utilization by base pairing and causes a miscoding of DNA. Alkylating agents are cell cycle-nonspecific. Alkylating agents work by three different mechanisms all of which achieve the same end result - disruption of DNA function and cell death.

Chlorambucil Absorption

No information avaliable

Chlorambucil side effects and Toxicity

No information avaliable

Chlorambucil Patient Information

No information avaliable

Chlorambucil Organisms Affected

Humans and other mammals