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Cerubidine Brand names, Cerubidine Analogs

Cerubidine Brand Names Mixture

  • No information avaliable

Cerubidine Chemical_Formula


Cerubidine RX_link


Cerubidine fda sheet


Cerubidine msds (material safety sheet)

Cerubidine MSDS

Cerubidine Synthesis Reference

J. P. Parsh et al. J. Pharm. Sci. 56, 1691 (1967);

Cerubidine Molecular Weight

527.52 g/mol

Cerubidine Melting Point

208-209 oC

Cerubidine H2O Solubility

39.2 mg/L

Cerubidine State


Cerubidine LogP


Cerubidine Dosage Forms

Powder for solution; Suspension

Cerubidine Indication

For remission induction in acute nonlymphocytic leukemia (myelogenous, monocytic, erythroid) of adults and for remission induction in acute lymphocytic leukemia of children and adults.

Cerubidine Pharmacology

Daunorubicin is an antineoplastic in the anthracycline class. General properties of drugs in this class include: interaction with DNA in a variety of different ways including intercalation (squeezing between the base pairs), DNA strand breakage and inhibition with the enzyme topoisomerase II. Most of these compounds have been isolated from natural sources and antibiotics. However, they lack the specificity of the antimicrobial antibiotics and thus produce significant toxicity. The anthracyclines are among the most important antitumor drugs available. Doxorubicin is widely used for the treatment of several solid tumors while daunorubicin and idarubicin are used exclusively for the treatment of leukemia. Daunorubicin may also inhibit polymerase activity, affect regulation of gene expression, and produce free radical damage to DNA. Daunorubicin possesses an antitumor effect against a wide spectrum of tumors, either grafted or spontaneous. The anthracyclines are cell cycle-nonspecific.

Cerubidine Absorption

No information avaliable

Cerubidine side effects and Toxicity

LD50=20 mg/kg (mice, IV); LD50=13 mg/kg (rat, IV)

Cerubidine Patient Information

Cerubidine Organisms Affected

Humans and other mammals