Senior
Category
Senior Brand names, Senior Analogs
Senior Brand Names Mixture
No information avaliable
Senior Chemical_Formula
C10H14O4
Senior RX_link
http://www.rxlist.com/cgi/generic2/guaifen.htm
Senior fda sheet
Senior msds (material safety sheet)
Senior Synthesis Reference
No information avaliable
Senior Molecular Weight
198.216 g/mol
Senior Melting Point
78.5 oC
Senior H2O Solubility
50 mg/mL
Senior State
Solid
Senior LogP
0.95
Senior Dosage Forms
Liquid; Powder for solution; Syrup; Tablet
Senior Indication
Used to assist the expectoration of phlegm from the airways in acute respiratory tract infections.
Senior Pharmacology
Guaifenesin is an expectorant which increases the output of phlegm (sputum) and bronchial secretions by reducing adhesiveness and surface tension. The increased flow of less viscous secretions promotes ciliary action and changes a dry, unproductive cough to one that is more productive and less frequent. By reducing the viscosity and adhesiveness of secretions, guaifenesin increases the efficacy of the mucociliary mechanism in removing accumulated secretions from the upper and lower airway.
Senior Absorption
Rapidly absorbed from the GI tract
Senior Toxicity
LD50 1510 mg/kg (rat, oral)
Senior Patient Information
No information avaliable
Senior Organisms Affected
Humans and other mammals
