Guaiacyl_glyceryl_ether
Category
Guaiacyl_glyceryl_ether Brand names, Guaiacyl_glyceryl_ether Analogs
Guaiacyl_glyceryl_ether Brand Names Mixture
No information avaliable
Guaiacyl_glyceryl_ether Chemical_Formula
C10H14O4
Guaiacyl_glyceryl_ether RX_link
http://www.rxlist.com/cgi/generic2/guaifen.htm
Guaiacyl_glyceryl_ether fda sheet
Guaiacyl_glyceryl_ether msds (material safety sheet)
Guaiacyl_glyceryl_ether Synthesis Reference
No information avaliable
Guaiacyl_glyceryl_ether Molecular Weight
198.216 g/mol
Guaiacyl_glyceryl_ether Melting Point
78.5 oC
Guaiacyl_glyceryl_ether H2O Solubility
50 mg/mL
Guaiacyl_glyceryl_ether State
Solid
Guaiacyl_glyceryl_ether LogP
0.95
Guaiacyl_glyceryl_ether Dosage Forms
Liquid; Powder for solution; Syrup; Tablet
Guaiacyl_glyceryl_ether Indication
Used to assist the expectoration of phlegm from the airways in acute respiratory tract infections.
Guaiacyl_glyceryl_ether Pharmacology
Guaifenesin is an expectorant which increases the output of phlegm (sputum) and bronchial secretions by reducing adhesiveness and surface tension. The increased flow of less viscous secretions promotes ciliary action and changes a dry, unproductive cough to one that is more productive and less frequent. By reducing the viscosity and adhesiveness of secretions, guaifenesin increases the efficacy of the mucociliary mechanism in removing accumulated secretions from the upper and lower airway.
Guaiacyl_glyceryl_ether Absorption
Rapidly absorbed from the GI tract
Guaiacyl_glyceryl_ether Toxicity
LD50 1510 mg/kg (rat, oral)
Guaiacyl_glyceryl_ether Patient Information
No information avaliable
Guaiacyl_glyceryl_ether Organisms Affected
Humans and other mammals
