Glyceryl_guaiacolate
Category
Glyceryl_guaiacolate Brand names, Glyceryl_guaiacolate Analogs
Glyceryl_guaiacolate Brand Names Mixture
No information avaliable
Glyceryl_guaiacolate Chemical_Formula
C10H14O4
Glyceryl_guaiacolate RX_link
http://www.rxlist.com/cgi/generic2/guaifen.htm
Glyceryl_guaiacolate fda sheet
Glyceryl_guaiacolate msds (material safety sheet)
Glyceryl_guaiacolate Synthesis Reference
No information avaliable
Glyceryl_guaiacolate Molecular Weight
198.216 g/mol
Glyceryl_guaiacolate Melting Point
78.5 oC
Glyceryl_guaiacolate H2O Solubility
50 mg/mL
Glyceryl_guaiacolate State
Solid
Glyceryl_guaiacolate LogP
0.95
Glyceryl_guaiacolate Dosage Forms
Liquid; Powder for solution; Syrup; Tablet
Glyceryl_guaiacolate Indication
Used to assist the expectoration of phlegm from the airways in acute respiratory tract infections.
Glyceryl_guaiacolate Pharmacology
Guaifenesin is an expectorant which increases the output of phlegm (sputum) and bronchial secretions by reducing adhesiveness and surface tension. The increased flow of less viscous secretions promotes ciliary action and changes a dry, unproductive cough to one that is more productive and less frequent. By reducing the viscosity and adhesiveness of secretions, guaifenesin increases the efficacy of the mucociliary mechanism in removing accumulated secretions from the upper and lower airway.
Glyceryl_guaiacolate Absorption
Rapidly absorbed from the GI tract
Glyceryl_guaiacolate Toxicity
LD50 1510 mg/kg (rat, oral)
Glyceryl_guaiacolate Patient Information
No information avaliable
Glyceryl_guaiacolate Organisms Affected
Humans and other mammals
