Guaiacuran
Category
Guaiacuran Brand names, Guaiacuran Analogs
Guaiacuran Brand Names Mixture
No information avaliable
Guaiacuran Chemical_Formula
C10H14O4
Guaiacuran RX_link
http://www.rxlist.com/cgi/generic2/guaifen.htm
Guaiacuran fda sheet
Guaiacuran msds (material safety sheet)
Guaiacuran Synthesis Reference
No information avaliable
Guaiacuran Molecular Weight
198.216 g/mol
Guaiacuran Melting Point
78.5 oC
Guaiacuran H2O Solubility
50 mg/mL
Guaiacuran State
Solid
Guaiacuran LogP
0.95
Guaiacuran Dosage Forms
Liquid; Powder for solution; Syrup; Tablet
Guaiacuran Indication
Used to assist the expectoration of phlegm from the airways in acute respiratory tract infections.
Guaiacuran Pharmacology
Guaifenesin is an expectorant which increases the output of phlegm (sputum) and bronchial secretions by reducing adhesiveness and surface tension. The increased flow of less viscous secretions promotes ciliary action and changes a dry, unproductive cough to one that is more productive and less frequent. By reducing the viscosity and adhesiveness of secretions, guaifenesin increases the efficacy of the mucociliary mechanism in removing accumulated secretions from the upper and lower airway.
Guaiacuran Absorption
Rapidly absorbed from the GI tract
Guaiacuran Toxicity
LD50 1510 mg/kg (rat, oral)
Guaiacuran Patient Information
No information avaliable
Guaiacuran Organisms Affected
Humans and other mammals