Guaiphesin
Category
Guaiphesin Brand names, Guaiphesin Analogs
Guaiphesin Brand Names Mixture
No information avaliable
Guaiphesin Chemical_Formula
C10H14O4
Guaiphesin RX_link
http://www.rxlist.com/cgi/generic2/guaifen.htm
Guaiphesin fda sheet
Guaiphesin msds (material safety sheet)
Guaiphesin Synthesis Reference
No information avaliable
Guaiphesin Molecular Weight
198.216 g/mol
Guaiphesin Melting Point
78.5 oC
Guaiphesin H2O Solubility
50 mg/mL
Guaiphesin State
Solid
Guaiphesin LogP
0.95
Guaiphesin Dosage Forms
Liquid; Powder for solution; Syrup; Tablet
Guaiphesin Indication
Used to assist the expectoration of phlegm from the airways in acute respiratory tract infections.
Guaiphesin Pharmacology
Guaifenesin is an expectorant which increases the output of phlegm (sputum) and bronchial secretions by reducing adhesiveness and surface tension. The increased flow of less viscous secretions promotes ciliary action and changes a dry, unproductive cough to one that is more productive and less frequent. By reducing the viscosity and adhesiveness of secretions, guaifenesin increases the efficacy of the mucociliary mechanism in removing accumulated secretions from the upper and lower airway.
Guaiphesin Absorption
Rapidly absorbed from the GI tract
Guaiphesin Toxicity
LD50 1510 mg/kg (rat, oral)
Guaiphesin Patient Information
No information avaliable
Guaiphesin Organisms Affected
Humans and other mammals
