Guaiphenesin
Category
Guaiphenesin Brand names, Guaiphenesin Analogs
Guaiphenesin Brand Names Mixture
No information avaliable
Guaiphenesin Chemical_Formula
C10H14O4
Guaiphenesin RX_link
http://www.rxlist.com/cgi/generic2/guaifen.htm
Guaiphenesin fda sheet
Guaiphenesin msds (material safety sheet)
Guaiphenesin Synthesis Reference
No information avaliable
Guaiphenesin Molecular Weight
198.216 g/mol
Guaiphenesin Melting Point
78.5 oC
Guaiphenesin H2O Solubility
50 mg/mL
Guaiphenesin State
Solid
Guaiphenesin LogP
0.95
Guaiphenesin Dosage Forms
Liquid; Powder for solution; Syrup; Tablet
Guaiphenesin Indication
Used to assist the expectoration of phlegm from the airways in acute respiratory tract infections.
Guaiphenesin Pharmacology
Guaifenesin is an expectorant which increases the output of phlegm (sputum) and bronchial secretions by reducing adhesiveness and surface tension. The increased flow of less viscous secretions promotes ciliary action and changes a dry, unproductive cough to one that is more productive and less frequent. By reducing the viscosity and adhesiveness of secretions, guaifenesin increases the efficacy of the mucociliary mechanism in removing accumulated secretions from the upper and lower airway.
Guaiphenesin Absorption
Rapidly absorbed from the GI tract
Guaiphenesin Toxicity
LD50 1510 mg/kg (rat, oral)
Guaiphenesin Patient Information
No information avaliable
Guaiphenesin Organisms Affected
Humans and other mammals
