Amonidrin
Category
Amonidrin Brand names, Amonidrin Analogs
Amonidrin Brand Names Mixture
No information avaliable
Amonidrin Chemical_Formula
C10H14O4
Amonidrin RX_link
http://www.rxlist.com/cgi/generic2/guaifen.htm
Amonidrin fda sheet
Amonidrin msds (material safety sheet)
Amonidrin Synthesis Reference
No information avaliable
Amonidrin Molecular Weight
198.216 g/mol
Amonidrin Melting Point
78.5 oC
Amonidrin H2O Solubility
50 mg/mL
Amonidrin State
Solid
Amonidrin LogP
0.95
Amonidrin Dosage Forms
Liquid; Powder for solution; Syrup; Tablet
Amonidrin Indication
Used to assist the expectoration of phlegm from the airways in acute respiratory tract infections.
Amonidrin Pharmacology
Guaifenesin is an expectorant which increases the output of phlegm (sputum) and bronchial secretions by reducing adhesiveness and surface tension. The increased flow of less viscous secretions promotes ciliary action and changes a dry, unproductive cough to one that is more productive and less frequent. By reducing the viscosity and adhesiveness of secretions, guaifenesin increases the efficacy of the mucociliary mechanism in removing accumulated secretions from the upper and lower airway.
Amonidrin Absorption
Rapidly absorbed from the GI tract
Amonidrin Toxicity
LD50 1510 mg/kg (rat, oral)
Amonidrin Patient Information
No information avaliable
Amonidrin Organisms Affected
Humans and other mammals
