Guaiphenesine
Category
Guaiphenesine Brand names, Guaiphenesine Analogs
Guaiphenesine Brand Names Mixture
No information avaliable
Guaiphenesine Chemical_Formula
C10H14O4
Guaiphenesine RX_link
http://www.rxlist.com/cgi/generic2/guaifen.htm
Guaiphenesine fda sheet
Guaiphenesine msds (material safety sheet)
Guaiphenesine Synthesis Reference
No information avaliable
Guaiphenesine Molecular Weight
198.216 g/mol
Guaiphenesine Melting Point
78.5 oC
Guaiphenesine H2O Solubility
50 mg/mL
Guaiphenesine State
Solid
Guaiphenesine LogP
0.95
Guaiphenesine Dosage Forms
Liquid; Powder for solution; Syrup; Tablet
Guaiphenesine Indication
Used to assist the expectoration of phlegm from the airways in acute respiratory tract infections.
Guaiphenesine Pharmacology
Guaifenesin is an expectorant which increases the output of phlegm (sputum) and bronchial secretions by reducing adhesiveness and surface tension. The increased flow of less viscous secretions promotes ciliary action and changes a dry, unproductive cough to one that is more productive and less frequent. By reducing the viscosity and adhesiveness of secretions, guaifenesin increases the efficacy of the mucociliary mechanism in removing accumulated secretions from the upper and lower airway.
Guaiphenesine Absorption
Rapidly absorbed from the GI tract
Guaiphenesine Toxicity
LD50 1510 mg/kg (rat, oral)
Guaiphenesine Patient Information
No information avaliable
Guaiphenesine Organisms Affected
Humans and other mammals
