Gvaja
Category
Gvaja Brand names, Gvaja Analogs
Gvaja Brand Names Mixture
No information avaliable
Gvaja Chemical_Formula
C10H14O4
Gvaja RX_link
http://www.rxlist.com/cgi/generic2/guaifen.htm
Gvaja fda sheet
Gvaja msds (material safety sheet)
Gvaja Synthesis Reference
No information avaliable
Gvaja Molecular Weight
198.216 g/mol
Gvaja Melting Point
78.5 oC
Gvaja H2O Solubility
50 mg/mL
Gvaja State
Solid
Gvaja LogP
0.95
Gvaja Dosage Forms
Liquid; Powder for solution; Syrup; Tablet
Gvaja Indication
Used to assist the expectoration of phlegm from the airways in acute respiratory tract infections.
Gvaja Pharmacology
Guaifenesin is an expectorant which increases the output of phlegm (sputum) and bronchial secretions by reducing adhesiveness and surface tension. The increased flow of less viscous secretions promotes ciliary action and changes a dry, unproductive cough to one that is more productive and less frequent. By reducing the viscosity and adhesiveness of secretions, guaifenesin increases the efficacy of the mucociliary mechanism in removing accumulated secretions from the upper and lower airway.
Gvaja Absorption
Rapidly absorbed from the GI tract
Gvaja Toxicity
LD50 1510 mg/kg (rat, oral)
Gvaja Patient Information
No information avaliable
Gvaja Organisms Affected
Humans and other mammals